The Physical, Psychological and Relational Benefits of Prayer

By: Jen McWaters, Psy.D. | July 25, 2025

Prayer has long been a core spiritual practice, and growing research in neuroscience and psychology suggests it may also be a powerful tool for mental, emotional, and even physical health. While science is still uncovering the full mechanisms behind prayer’s effects, the evidence suggests it can help reduce stress, improve focus, and support emotional resilience. In our face-paced, digitally dominated culture, I believe that practices like prayer and stillness are more important than ever for reclaiming the health of our soul, spirit, and body.

Prayer and Brain Health

Dr. Andrew Newberg, a neuroscientist and pioneer in the field of neurotheology, has extensively studied the effects of religious and spiritual practices, including prayer. His SPECT scan research shows that practices like prayer and meditation activate the prefrontal cortex – the region of the brain responsible for decision-making, attention, and self-regulation (Newberg et al., 2001).

Prayer has also been shown to reduce activity in the amygdala, the brain’s fear center, which may promote a greater sense of calm and security (Newberg & Waldman, 2009). These findings help explain why many individuals report feeling more focused and emotionally balanced after engaging in contemplative or devotional practices.

Prayer and Emotional Resilience

Prayer is often used as a coping mechanism during times of stress, and research supports its benefits for emotional well-being. A 2004 study in the Journal of Health Psychology found that individuals who viewed prayer as a collaborative process – seeing themselves as working with God rather than being helpless, reported better mental and physical health outcomes (Pargament et al., 2004).

Prayer may also contribute to:

  • Reduced perceived stress
  • Increased sense of hope and gratitude
  • Greater emotional regulation

Prayer is not a passive activity, it is an active process that offers a sense of connection, purpose, and meaning – all of which are protective factors against psychological distress.

Physical Health Benefits of Prayer and Religious Practice

Although the physical effects of prayer alone are still being investigated, broader research on religious and spiritual involvement (R/SI) suggests meaningful health benefits. A comprehensive review by Koenig et al. (2012), found that R/SI is associated with:

  • Lower blood pressure and heart rate
  • Improved immune function
  • Better sleep quality
  • Reduced risk of depression and substance abuse

These benefits are thought to arise from a combination of behavioral factors (e.g., lower substance use), psychological factors (e.g., reduced anxiety), and social factors (e.g., greater community support).

The Relational Impact of Prayer

A study by Fincham et al. (2008) at Florida State University explored the effects of partner-focused prayer in romantic relationships. Their findings showed that individuals who prayed for their partner experienced:

  • Increased relationship satisfaction
  • Improved regulation of negative emotions
  • Reduced tendencies toward aggression and resentment

In this context, prayer appeared to cultivate empathy and selflessness – qualities that help strengthen relational bonds.

How Prayer May Work: Current Scientific Theories

While the effects of prayer can be deeply personal and spiritual, scientists have proposed several mechanisms through which it may influence the brain and body:

  • Stress Reduction: Prayer may help lower cortisol levels by promoting calmness and reducing rumination.
  • Enhanced Attention and Focus: Repetitive prayer or contemplative practices may strengthen neural pathways involved in sustained attention.
  • Positive Cognitive Framing: Prayer often involves gratitude, surrender, or hope, which can shift mental outlook and buffer against negative thinking.
  • Parasympathetic Activation: Quiet, focused prayer can help activate the parasympathetic nervous system, known as the body’s “rest and digest” mechanism, thereby reducing physiological stress responses.

Deepen Your Prayer Life: Reflective Journal Prompts to Cultivate Spiritual Awareness

If you’d like to begin or enrich your spiritual practice through prayer, journaling can be a powerful companion. It helps you recognize patterns, clarify your thoughts, and tune into your inner experience. Try setting aside 5–10 minutes after prayer to reflect on the following questions:

    1. What did I bring to prayer today; emotionally, mentally, or physically?
    2. Did I feel a sense of connection, peace, or clarity during or after prayer? If so, what may have contributed to that?
    3. What thoughts, images, or impressions stood out to me while I was praying?
    4. What do I need to release, surrender, or trust in this season of life?
    5. What am I most grateful for today? How can I carry that into my actions and mindset?

How to Integrate Prayer into Your Life

If you’re feeling overwhelmed, emotionally drained, or disconnected, prayer can be a grounding practice to help restore clarity and calm. Whether you identify as religious or spiritual in a broader sense, prayer can serve as a daily ritual to pause, reflect, and connect with something greater than yourself. These practices not only uplift your mindset; they can also support your physical well-being and foster personal growth.

If you’re struggling and not sure where to turn, know that you don’t have to go through it alone. The team at Therapy Changes is here to support you with compassion, expertise, and care. Contact us today to schedule an appointment with one of our talented therapists – we’re honored to walk alongside you on your journey toward healing and growth.

 

References
Fincham, F. D., Beach, S. R. H., Lambert, N. M., Stillman, T. F., & Braithwaite, S. R. (2008). Spiritual behaviors and relationship satisfaction: A longitudinal examination. Psychology of Religion and Spirituality, 1(S), 1–10. https://doi.org/10.1037/1941-1022.S.1.1
Koenig, H. G., King, D. E., & Carson, V. B. (2012). Handbook of Religion and Health (2nd ed.). Oxford University Press.
Newberg, A. B., D’Aquili, E. G., & Rause, V. (2001). Why God Won’t Go Away: Brain Science and the Biology of Belief. Ballantine Books.
Newberg, A. B., & Waldman, M. R. (2009). How God Changes Your Brain. Ballantine Books.
Pargament, K. I., Smith, B. W., Koenig, H. G., & Perez, L. (2004). Patterns of positive and negative religious coping with major life stressors. Journal of Health Psychology, 9(6), 713–730. https://doi.org/10.1177/1359105304045366

 

 

 

Photo by Ben White on Unsplash

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